and Alternative Medicine, Ministry of Public Health Alternative Medicine ” (DTAM) was established as a new department under the Ministry …
Executive Summary of Integrative Medicine at WFUSM January 2004 June 30, 2005 Compiled by Kathi J Kemper, MD, MPH Caryl J Guth Chair for Holistic and Integrative Medicine Professor, Departments of Pediatrics, Public Health Sciences, and Family Medicine Integrative Medicine is the practice of medicine that reaffirms the importance of the relationship between practitioner and patient, focuses on the whole person, is informed by evidence, and makes use of all appropriate therapeutic approaches, healthcare professionals and disciplines to achieve optimal health and healing Consortium of Academic Health Centers for Integrative Medicine, 2005 Complementary and alternative medical CAM therapies are some of the tools used in the practice of integrative medicine The National Institutes of Healths National Center for Complementary and Alternative Medicine NIH NCCAM defines five domains of CAM: biologically based therapies eg, herbs and dietary supplements, mind-body interventions eg, meditation
and music, biofield therapies eg, Reiki and Healing Touch, manipulative and bodybased methods eg, massage and alternative medical systems More than 40 of Americans use CAM, spending 36 - 47 billion annually 12 - 20 billion out of pocket; in 1997 more was spent out of pocket on CAM than on hospital care in the US CAM use is higher in groups suffering from chronic or incurable conditions, such as those seeking hospital and specialty care Research in this field includes basic, clinical, educational, and health services research More than 80 WFUSM faculty are pursuing academic work in Integrative Medicine, with over 25 million in research funding and 115 peer-reviewed publications Funding sources include NIH, foundations, industry and philanthropy Educational efforts encompass all levels from PA and medical students through faculty development, 20 review articles, chapters and books, and 90 talks given locally, regionally, nationally and internationally Topics of interest include
epidemiology and health services, communication and clinician-patient relationships, herbs and dietary supplements, biofield therapies, mind-body therapies, ethical and legal issues, and spirituality Wake Forest is the coordinating institution for the North Carolina Academic Alliance for Integrative Medicine and is one of 25 medical schools in the Consortium of Academic Health Centers for Integrative Medicine Given the substantial and diverse research and educational efforts in Integrative Medicine underway, a Center is urgently needed to facilitate and coordinate existing programs; to foster cross-disciplinary collaborative models for academic success in alignment with the NIH roadmap; to build on existing institutional strengths; to attract highly accomplished and promising faculty and trainees; and to develop innovative educational and research initiatives such as PhD programs and fellowship training in Integrative Medicine that will enhance the overall mission of the medical
center
Executive Summary of Integrative Medicine at WFUSM 1 Recent Growth in Integrative Medicine at WFUSM 3 Standing Committees and Task Forces N9 3 Research Funding N82 5 Research Publications, peer reviewed N104 16 Review articles, chapters and books N21 24 Abstracts N14 26 Holistic and Integrative Medical Education 28 Local CME/Grand Rounds/NW AHEC Presentations to Professionals N22 31 Regional, National and International Presentations N42 33 Clinical Outreach N12 37 Community Outreach N18 38 National Advisory Boards 40 Editorial Boards 40 Honors: 40
2 August 1, 2005
Recent Growth in Integrative Medicine at WFUSM
Research Projects Funded 90 80 70 60 50 40 30 20 10 0 2003 2004 2005
Research Funding
30,000,000 25,000,000 20,000,000 15,000,000 10,000,000 5,000,000
0
2003 2004 2005
Publications peer reviewed articles, chapters, books 160 140 120 100 80 60 40 20 0 2003 2004 2005
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Standing Committees and Task Forces N8
CAM in the Community Committee
Facilitator - Arcury Family Medicine Started 10/01 Projects - Seminar Series; BestHealth lecture series; BestHealth internet site; CAM Community Mixer Distribution List: N200 Committee for Holistic and Integrative Medical Education CHIME Chairs - Ober Internal Medicine and Kemper Pediatrics Started 4/03 Activities- updated cases for Phase IA; updated med student web site; elective Distribution List: N 46 Subcommittee on PhD Program in Integrative Medicine Chairs: Ski Chilton Phys/Pharm, Kemper Peds and Shumaker Office Research 2005Consortium for Academic Health Centers for Integrative Medicine CAHCIM NEW WFUSM accepted 2004 Clinical Working Group Delegate: Feldman Education Working Group Delegates: Ober and Lischke Research Working Group Delegates: Arcury and Dailey Executive Steering Committee Delegate: Kemper Council on Bioenergetic Healing Research CBH Chair - Kemper Pediatrics Activities: Research, Education, Clinical Services volunteer Distribution list: N 51 Council on
Mind-Body Medicine NEW Chair Feldman Neuropsychology and Kemper Pediatrics Started 2004 Distribution list: N 17 Herb and Dietary Supplement Task Force HDSTF Chairs - Kemper Pediatrics and Schwatrz Cancer Center Started 2003 Activities: Booke visiting professors Distribution list: N 81 Nutrition Epidemiology Research and Applications Journal Club Facilitator -Vitolins Started 1996 Activities monthly journal club Co-sponsors Booke visiting professors Spirituality and Healing Facilitator Mark Jensen, Pastoral Care
4 August 1, 2005
Research Funding N82 Biofield therapies/Spirituality: Acupuncture, Healing Touch, Qigong, Prayer
PI: Avis Source: NIH/NCI Total: 300,000 Term: 06/18/2004-05/31/2006 Status: Funded Title: Acupuncture treatment for menopausal hot flashes PI: Kemper KJ Source: Komen Foundation Total: 4,000 Term: 2/15/04-1/31/05 Status: Funded Title: Biofield-Touch Therapy for Breast Cancer Patients Rosalyn Bruyere, Visiting Professor
Biomechanical
PI: Karlson K, Kemper KJ,
Rubin B Total: Status: Unfunded Title: Preliminary study regarding massage therapy in cystic fibrosis patients
Cancer CAM Support Overall awarded amount - 1,374,651
PI: Dailey M Total: Included in above total Status: Funded Title: Mindfulness-Based Stress Reduction in Patients with Non-Small Cell Lung Cancer CA 12197-S1 Renewed 02/18/04 PI: Hall Total: Included in above total Status: Submitted and Pending Title: IRB Approval Date for Phase II Trial of Lycopene for Biochemical Relapse of Prostate Cancer Following Definitive Local Therapy PI: Koumenis C Total: Included in above total Status: Project completed: ACUC protocol termination 09/04 Title: Bee Propolis An Active Ingredient in CAPE:
5 August 1, 2005
PI: Naughton M, Shaw E Total: Included in above total Status: Funded Title: Phase II Study of St Johns Wort for the Treatment of Hot Flushes in Women with a History of Breast Cancer PI: Pitovski D Total: Included in above total Status: Protocol Pending Title: Efficacy and safety
of propolis in preventing radiation-induced mucositis: A randomized double blind pilot study PI: Robbins M Total: Included in above total Status: Funded Title: Mediated Modulated of Radiation Induced Cognitive Impairment in the Rat PI: Schwartz G Total: Included in above total Status: Completed Closed to accrual 09/17/04 Title: IRB Approval Date for Effects of fish oil supplementation on PSA levels in healthy men PI: Schwartz, G Source: NCI/NCCAM Total: 74,905 Term: 03/01/1996-03/31/2004 Status: Funded Title: Orthomolecular Vitamin D3 in Low Risk Myelodysplastic Syndrome: An open-label clinical trial PI: Wallin R Total: Included in above total Status: Funded Title: Vitamin K, Bone and Arterial Calcification
Communication, Clinician-Patient Relationship and Cultural Competence
PI: Crandall C, Family Community Medicine, Total: 398,520 Source: PHS DHHS Status: Funded Term: 2003-2006 Title: Creating a Comprehensive Core Communications Curriculum PI: Marion G, Family and Community
Medicine, Total: 779,450 Source: PHS DHHS Status: Funded Period: 2004-2007 Total Funds: 779,450 Title: Advancing Communication, Cultural Competency and Diversity 6 August 1, 2005
Epidemiology/Health Services
PI: Arcury T Source: R21 AT002241 NCCAM Total: 312,000 Term: 2004-2006 Status: Funded Title: Differences in CAM use Among Minority Older Adults PI: Grzywacz J Source: NIH/NCCAM Total: 359,063 Term: 1/1/2004-12/31/2005 Status: Funded Title: Conceptual approach to life-course variation in CAM use
Herbs and Dietary Supplements
PI: Adams M Source: NIH/NILBI Total: 1,148,000 Term: 4/1/2000-3/31/2009 Status: Funded Title: Dietary Soy Supplements Cardioprotective Mechanisms PI: Adams M Source: DHHS Total: 287,000 Term: 4/1/2005-3/31/2006 Status: Funded Title: Dietary Soy Supplements: Cardioprotective Mechanisms PI: Bowden D Source: University of Colorado Total: 36,772 Term: 7/1/2004-6/30/2005 Status: Funded Title: Effects of Vitamin D Genes on Measures of Insulin Secretion, Insulin
Sensitivity, and Adiposity PI: Burke G Source: University of Pittsburgh Total: 416,192 Term: 9/30/1999-07/31/2005 Status: Funded Title: Ginkgo Biloba Prevention Trial in Older Adults Clinical Center PI: Burke G, Vitolins M Source: CDC: TS 501-16/16 Total: 138,210 Term: 10/01/2000-09/30/2004 Status: Funded Title: Lipid lowering from soy protein and isoflavone extract PI: Chen Y Source: National Institute of Health Total: 294,461 Term: 4/1/2004-5/31/2005 Status: Funded Title: Mechanisms of Fish Oil Supplements in Prevention of Prostate Cancer 7 August 1, 2005
PI: Chilton F Source: Dept of Health and Human Services Total: 7,500,000 Term: 4/1/2005-3/31/2006 Status: Funded Title: The Wake Forest and Harvard Center for Botanical Lipids PI: Clarkson T Total: 250,000 Status: Funded Title: Soy/HRT Combinations Source: Protein Technologies Term: 6/25/2002-5/31/2005
PI: Cline M Source: NIH/NCCAM Total: 100,000 Term: 09/01/2003-08/30/2004 Status: Funded Title: Effects of dietary soy on
biomarkers in prostate cancer PI: Cline M Total: 298,486 Status: Funded Title: Soy and estrogen interactions in the breast Source: NIH/NCCAM Term: 09/18/2000-06/30/2004
PI: Cramer S Source: National Institutes of Health Total: 922,500 Term: 9/30/2004-8/31/2009 Status: Funded Title: Vitamin D and Soy Isoflavone Inhibition of LCAT, Lipids and Atherosclerosis PI: Cramer S Source: Army Med RD Command Total: 179,375 Term: 08/31/2004-11/30/2007 Status: Funded Title: Vitamin D and Genistein Inhibition of Prostate Growth PI: Edwards I Source: American Institute for Cancer Research Total: 150,000 Term: 07/31/2005-06/30-2007 Status: Funded Title: Fatty Acids, Proteoglycans and Breast Cancer PI: Edwards I Total: Status: Submitted and Pending Title: Syndecan 1 regulation by n-3 PUFA Source: NIH/NCI Term:
PI: Furberg C, Rapp S Source: University of Pittsburg Total: 297,493 Term: 9/30/1999 - 7/31/2005 Status: Funded Title: Ginkgo Biloba prevention Trial in Older Induviduals - Clinical Coordinating
Center 8 August 1, 2005
PI: Garcia S
Total: 47,296 Status: Funded Title: Manganese Neurotoxicity in Developing Non-Deficient Rats PI: Hu J Source: National Cancer Institute Total: 215,250 Term: 7/10/2003-6/30/2006 Status: Funded Title: Effects of Fruit and Vegetable Extracts on Cancer Markers PI: Kaplan JR Source: NIH Total: 690,334 Term: 1/1/2005-12/31/2009 Status: Funded Title: Soy, Life Stage, Stress and Atherosclerosis in Females PI: Kemper KJ Source: Private donor Total: 10,000 Term: 09/1/2003-8/31/2004 Status: Funded Title: Visiting professors in herbs and dietary supplements
Source: National Institute of Environmental Health Sciences NIEHS Term: 9/30/2003-9/29/2005
PI: Kemper KJ Source: Fullerton Foundation Total: 14,589 Term: 12/01/2004-11/30/2005 Status: Funded Title: Feasibility of educating South Carolina clinicians about herbs and supplements by internet PI: Kemper KJ Source: Revival Soy Total: 6,636 Term: 09/01/2004-8/31/2005 Status: Submitted and Pending Title: Use
of soy and other complementary therapies for nausea and vomiting of pregnancy PI: Kemper KJ Source: Private Donor Total: 15,000 Term: 9/1/2004-8/31/2005 Status: Funded Title: Visiting professors in herbs and dietary supplements PI: Kemper KJ Source: NIH/NLM RO1 Total: 365,552 Term: 2/1/2004-1/31/2006 Status: Funded Title: Evaluating an Internet-Based Curriculum About Herbs and Dietary Supplements PI: Koumenis C Source: NIH Total: Term: 4/1/2005-3/30/2009 Status: Submitted and Pending Title: Phenolic antioxidants as tumor/radio/chemosensitizers: properties of CAPE and curcumin in vitro and in vivo 9 August 1, 2005
PI: Kute T Source: Vaughn-Jordon Total: 40,000 Term: 6/14/2004-6/13/2007 Status: Funded Title: Use of Soy products to Enhance Herceptin Treatment for Cancer Patients PI: Laurienti P Source: NIH Total: 386,883 Term: 4/01/2005-01/31/2006 Status: Funded Title: Effective caffeine on function and perfusion MRI PI: Lee R Source: Southwest Oncology Group Total: 3,154 Term:
6/1/1993-5/31/2004 Status: Funded Title: Selenium and Vitamin E Chemoprevention Trial: Clinical Center PI: Molnar I, Schwartz G Source: NCI/NCCAM Total: 74,905 Term: 1/2003-12/2005 Status: Funded Title: Orthomolecular Vitamin D3 in Treatment of Patients with MDS CA 012197-S1 PI: Parks J Total: 225,000 Status: Funded Title: Dietary PUFA effects of LCAT reactivity PI: Parks J Total: 34,999 Status: Funded Title: LCAT Lipids and Atherosclerosis PI: Parks J, Chen Y Total: 358,750 Status: Funded Title: LCAT Lipids and Atherosclerosis Source: NIH NHLBI Term: 03/01/1996-03/31/2004
Source: WFUSM Venture Grant Term: 03/12/2004-03/31/2005
Source: NHLBI Term: 1/1/2005-12/31/2009
PI: Robertson J VTech, WFUSM Hess, Robbins, Shaw, Shaw Source: Equine Foundation Total: 10,000 Term: 6/1/2004-5/31/2005 Status: Funded Title: Evaluation of Therapeutic Grade Essential Plant Oils for treatment of Equine Sarcoids, Melanomas, Squamous Cell Carcinoma, in vitro and kinetic studie
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PI:
Robertson J VTech, WFUSM Hess, Robbins, Shaw, Shaw Source: WFUBMC Total: 9,200 Term: 4/1/2004-3/31/2005 Status: Funded Title: Phase I-II clinical trial of therapeutic grade essential plant oils for spontaneous cutaneous tumors in dogs and horses PI: Schwartz G Source: NCI/NCCAM Total: 90,000 direct costs Term: 12/2003-11/2004 Status: Funded Title: Do dietary supplements of antioxidants and zinc reduce serum cadmium levels in smokers? PI: Shaw E Source: NCI/ CCCWFU CCOP Total: 310,707 Term: 03/2001- 04/2005 Status: Funded Title: Phase III Double Blind Randomized Trial comparing sertraline and hypricum perforatum in cancer patients with mild to moderate depression PI: Shaw E Source: Total: Term: Status: Pending Title: Phase II Studies of donepezil and ginkgo biloba in irradiated brain tumor patients PI: Shaw E Source: NCI/NIH Total: 15,000 Term: Status: Title: The in vitro and in vivo efficacy of therapeutic grade essential oils PI: Shively C Source: United Soybean Board, Soy Health
Research Program Term: One-time award
Total: 10,000 Status: Funded Title: Effect of soy on behavior, mood and neural serotonergetic function of the female cynomolgus monkeys PI: Toole J
Total: 2,113,126 Status: Funded Title: Vitamin Intervention for Stroke Prevention VISP
Source: National Institute of Neurological Disorders and Stroke NINDS Term: 9/15/1996-7/31/2006
PI: Torti S Source: American Institute for Cancer Research Total: 82,500 Term: 1/31/2005-12/31/2006 Status: Funded Title: Iron and the Chemopreventative Activity of Curcumin 11 August 1, 2005
PI: Vitolins M Total: 38,636 Status: Funded Title: Soy Trial of the Prostate
Source: Ohio State University Term: 7/1/2002-3/31/2005
PI: Vitolins M Source: Total: Pending Term: Status: Pending Title: Randomized study of soy protein and effexor on vasomotor symptoms of men with prostate cancer PI: Wagner J Source: WFUSM Venture Grant Total: 15,000 Term: 5/19/2004-5/31/2005 Status: Funded Title: Mechanisms whereby dietary soy
protein improves insulin sensitivity in premenopausal monkeys PI: Wallin R Total: 322,875 Status: Funded Title: Vitamin K, Bone and Arterial Calcification Source: NIH Term: 7/1/2003-6/30/2007
PI: Westcott C Source: Adolor Total: 44,245 Term: 6/30/2005-7/19/2004 Status: Funded Title: Lipid HDL Reverse Cholesterol Transport in African Green Monkeys PI: Williamson J Source: NIH-NIA Total: 25,000 Term: 3/15/2005-3/14/2006 Status: Funded Title: Ginkgo Evaluation of Memory-Inflammation and Neuroimaging GEMINI PI: Kaplan J Source: NHLBI Total: 2,298,609 Term: 4/1/2003-3/31/2005 Status: Funded Title: Cardiovascular Benefits of Soy Phytoestrogens PI: Levine M Source: Penn State University Total: 130,050 Term: 10/6/2004-6/30/2005 Status: Funded Title: A Comparison of the Ability of Two Protein Ginger Products to Reduce the Delayed Nausea Following Chemotherapy
12 August 1, 2005
Legal, Ethical and Policy Issues
PI: Cohen M, Kemper KJ Source: Greenwall Foundation Total: 1,000 Term:
06/07/2004-06/06/2005 Status: Funded Title: Pediatric Use of Complementary Therapies by Parents: Ethical and Policy Choices
Lifestyle and Mind-Body
PI: Avis N Source: NCI/NCCAM Total: Term: Status: Pending Title: Yoga Intervention for Menopausal Hot Flashes PI: Dailey M, McCarty A Source: NCAA-IM Total: 3,000 Term: 9/2005 Status: Funded Title: Mindfulness-Based Stress Reduction MBSR for Overweight and Obesity in Adolescents PI: Danhauer SC Source: ACS Total: Term: continuation 1/1/2005-12/31/2005 Status: Funded Title: Restorative Yoga for Symptom Management Stress Reduction in Women with Breast Cancer PI: Danhauer SC Source: ACS institutional Total: 18,013 Term: 1/1/2004-12/31/2004 Status: Funded Title: Restorative Yoga for Symptom management and Stress Reduction in Women with Ovarian Cancer PI: Danhauer SC Source: NCAA-IM Total: 3,000 Term: 4/2004-3/2005 Status: Funded Title: Use of Music Guided Imagery to Reduce Anxiety Pain Perceived for Women Undergoing Colposcopy PI: Kelly E
Source: NCAA-IM Total: 3,000 Term: 2/1/2004-1/31/2005 Status: Funded Title: Impact of music on heart rate variability in pediatric oncology patients
13 August 1, 2005
PI: Kemper KJ Source: NIH NCCAM K24 Total: 455,155 Term: 02/1/2005-1/31/2006 Status: Funded Title: Heart rate variability in response to CAM in pediatrics PI: Kemper KJ Source: NIH NCCAM R21 Total: 215,250 Term: 4/1/2005-3/31/2007 Status: Funded Title: Harp Music: Effects on HRV, Cortisol and Activity PI: McCarty A, Dailey M Source: Consortium of Academic Health Centers for Integrative Medicine Term: 6/2005-5/2006
Total: 4,800 Status: Funded Title: Expanding Mind-Body Experiential Training
PI: Shively C Source: NIH/NIMH Total: 303,182 Term: 12/01/1998-11/30/2004 Status: Funded Title: Imaging Dopamine Function in Stress and Depression PI: Shively C Total: 48,269 Status: Funded Title: Social Status and Allostatic load Source: John D and Catherine T MacArthur Foundation Term: 07/01/2003-06/30/2004
Other
PI: Bonds
Source: NIH Total: Term: 1/1/06-12/30/08 Status: Pending Title: Trial of Advanced Strain Counterstrain for Reducing Overactive Bladder Syndrome PI: Kemper KJ Source: Kohlberg Foundation Total: 50,000 Term: 01/01/2004-12/30/2005 Status: Funded Title: North Carolina Academic Alliance for Integrative Medicine PI: Kemper KJ Source: NIH NCCAM Total: 1,606,708 Term: 10/01/2000-09/30/2005 Status: Funded Title: Center for Pediatric Integrative Medical Education
14 August 1, 2005
Spirituality
PI: Arcury T, Grzywacz J Source: NIH Total: 179,390 Term: 01/01/2006-12/30/2008 Status: Submitted and Pending Title: Spirituality Quality Dying: A Feasiblity Study of Prospective End-of-Life Research PI: Reifler B Total: 1,225,169 Status: Funded Title: Faith in Action, Phase II Source: Robert Wood Johnson Foundation Term: 2/1/2001-4/30/2006
PI: Suggs P Source: Jessie Bell DuPont Fund Total: 45,000 Term: 07/01/2002-06/30/2006 Status: Funded Title: Health and Spirituality in African-American
Congregation
15 August 1, 2005
Research Publications, peer reviewed N105 Biofield therapies/Spirituality: Acupuncture, Electromagnetic fields, Reiki, Healing Touch, Prayer
2004 Duflo F, Zhang Y, Eisenach JC Electrical field stimulation to study inhibitory mechanisms in individual sensory neurons in culture Anesthesiology, 2004;1003:740-743 Kemper KJ, Kelly EA Treating children with therapeutic and healing touch Pediatr Ann, 2004;334:248-252,254,255
2004
Clinician/Patient Relationship
2004 Bonds DE, Camacho F, Bell RA, Duren-Winfield VT, Anderson RT, Goff DC The association of patient trust and self-care among patients with diabetes mellitus [online only] BMC Fam Pract, 2004;51:article 26 Bonds DE, Foley KL, Dugan E, Hall MA, Extrom P An exploration of patients trust in physicians in training J Health Care Poor Underserved, 2004;152:294-306 Hall MA A corporate ethic of care in health care Seattle J Social Justice, 2004;31:417-428 Hall MA Caring, curing, and trust: a response to
Gatter Wake Forest Law Rev, 2004;392:447-451 Mihalko SL, Brenes GA, Farmer DF, Katula JA, Balkrishnan R, Bowen DJ Challenges and innovations in enhancing adherence Control Clin Trials, 2004;255:447-457 Thom DH, Hall MA, Pawlson LG Measuring patients trust in physicians when assessing quality of care Health Aff Millwood, 2004;234:124-132 Hall MA Can you trust a doctor you cant sue? DePaul Law Rev, 2005;542:303-313 Hall MA The importance of trust for ethics, law, and public policy Camb Q Healthc Ethics, 2005;142:156-167 Trachtenberg F, Dugan E, Hall MA How patients trust relates to their involvement in medical care J Fam Pract, 2005;544:344-352
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2004 Arcury TA, Preisser JS, Jr, Gesler WM, Sherman JE Complementary and Alternative Medicine Use Among Rural Residents in Western North Carolina Complementary Health Practice Review 92:93-102, 2004 Gardiner P, Dvorkin L, Kemper KJ Supplement use growing among children and
adolescents Pediatr Ann, 2004;334:227-232 Highfield ES, Kaptchuk TJ, Ott MJ Barnes L, Kemper KJ Availability of Acupuncture in the Hospitals of a Major Academic Medical Center: pilot study Complementary Therapies in Medicine, 2004, 113:177-83 16 August 1, 2005
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Kemper KJ, OConner K Pediatricians Recommendations for Complementary and Alternative Medical Therapies, Ambulatory Pediatrics, 2004;4:482-7 Arcury TA, Bell RA, Vitolins MZ, Quandt SA Rural older adults beliefs and behavior related to complementary and alternative medicine use Complement Health Pract Rev 2005:101:33-44 Bell RA, Suerken CK, Grzywacz JG, Lang W, Quandt SA, Arcury TA CAM use for health treatment among adults with diabetes in the US [abstract] 2005 Diabetes, 54Suppl 1:A242 Grzywacz JG, Lang W, Suerken C, Quandt SA, Bell RA, Arcury TA Age, race, and ethnicity in the use of complementary and alternative medicines CAM for health self management: Evidenced from the 2002 National Health Interview Survey
Journal of Aging and Health, in press Quandt SA, Chen H, Grzywacz JG, Bell RA, Lang W, Arcury TA Use of Complementary and Alternative Medicine by Persons with Doctor-Diagnosed Arthritis: Results of the NHIS Arthritis Care and Research, in press Grzywacz JG, Arcury TA, Bell RA, Lang W, Suerken C, Smith SL, Quandt SA Ethnic differences in elders home remedy use: sociostructural explainations American Journal of Health Behaviour, in press Highfield E, McLellan M, Kemper K, Risko W, Woolf AD Integration of Complementary and Alternative medicine in a Major Pediatric Teaching Hospital: An Initial Overview J Altern Complement Med, 2005: Apr;112:373-80 Sahmoun AE, Case LD, Jackson SA, Schwartz GG Cadmium and prostate cancer: a critical epidemiologic analysis Cancer Invest, 2005;233:256-263
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2004 Adams MR, Golden DL, Franke AA, Potter SM, Smith HS, Anthony MS Dietary soy Conglycinin 7S globulin inhibits atherosclerosis in
mice J Nutr 2004:1343: 511-516 Boyapati SM, Bostick RM, McGlynn KA, Fina MF, Roufail WM, Geisinger KR, Hebert JR, Coker A, Wargovich M Folate intake, MTHFR C677T polymorphism, alcohol consumption, and risk for sporadic colorectal adenoma United States Cancer Causes Control, 2004;155:493-501 Buss JL, Greene BT, Turner J, Torti FM, Torti SV, Iron chelators in cancer chemotherapy Curr Top Med Chem, 2004;415:1623-1635 Buss JL, Neuzil J, Ponka P Oxidative stress mediates toxicity of pyridoxal isonicotinoyl hydrazone analogs Arch Biochem Biophys, 2004;4211:1-9 Cesari M, Pahor M, Bartali B, Cherubini A, Penninx B, Williams GR, Atkinson H, Martin A, Guralnik JM Antioxidants and physical performance in elderly persons: the Invecchiare in Chianti InCHIANTI study Am J Clin Nutr, 2004;792: 289-294 Cline JM, Franke AA, Golden DL, Adams MR Effects of dietary aglycone isoflavones on the reproductive tract of male and female mice Toxicologic Pathology, 2004; 321:91-99 Cline JM, Franke A, Register TC,
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isoflavone aglycones on the reproductive tract of male and female mice Toxicol Path 2004 Jan-Feb;321:91-99 Connors N, Merrill D Antioxidants for prevention of preterm delivery Clin Obstet Gynecol, 2004;474:822-832 Dobson AW, Erikson KM, Aschner M Manganese neurotoxicity Ann N Y Acad Sci, 2004;1012:115-128 Edwards I, Berquin, I, Sun H, OFlaherty J, Daniel L, Thomas M, Rudel L, Wykle R, Chen Y Differential effects of omega-3 fatty acids to human cancer cells by lowdensity lipoproteins versus albumin 2004 Clinical Cancer Research 10: 827-8283 Erikson KM, Dobson AW, Dorman DC, Aschner M Manganese exposure and induced oxidative stress in the rat brain Sci Total Environ, 2004;334-335:409-416 Erikson KM, Dorman DC, Lash LH, Dobson AW, Aschner M Airborne manganese exposure differentially affects end points of
oxidative stress in an age- and sexdependent manner Biol Trace Elem Res, 2004;1001:49-62 Hantgan RR, Stahle MC, Connor JH, Lyles DS, Horita DA, Rocco M, Nagaswami C, Weisel JW, McLane MA The disintegrin echistatin stabilizes integrin alphaIIbbeta3s open conformation and promotes its oligomerization J Mol Biol, 2004;3425:1625-1636 Ilyasova D, Morrow JD, Ivanova A, Wagenknecht LE Epidemiological marker for oxidant status: comparison of the ELISA and the gas chromatography/mass spectrometry assay for urine 2,3-dinor-5,6-dihydro-15-F2t-isoprostane Ann Epidemiol, 2004;1410:793-797 Insull W Jr, McGovern ME, Schrott H, Thompson P, Crouse JR, Zieve F, Corbelli J Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: assessing all reasonable doses with innovative surface graph analysis Arch Intern Med, 2004;16410:1121-1127 John EM, Dreon DM, Koo J, Schwartz GG Residential sunlight exposure is associated with a decreased risk of prostate cancer J Steroid Biochem Mol Biol,
2004;89-90:549-552 Keung YK, Owen J Iron deficiency and thrombosis: literature review Clin Appl Thromb Hemost, 2004;104:387-391 Laniewski NG, Grayson JM Antioxidant treatment reduces expansion and contraction of antigen-specific CD8 T cells during primary but not secondary viral infection J Virol, 2004;7820:11246-11257 Molnar I, Kute T, Willingham MC, Schwartz GG 19-Nor-1-alpha, 25dihydroxyvitamin D2 paricalcitol exerts anticancer activity against HL-60 cells in vitro at clinically achievable concentrations Mozaffarian D, Rimm EB, Herrington DM Dietary fats, carbohydrate, and progression of coronary atherosclerosis in postmenopausal women Am J Clin Nutr, 2004;805:1175-1184 Porcelli PJ, Greene H, Adcock E A modified vitamin regimen for vitamin B2, A, and E administration in very-low-birth-weight infants J Pediatr Gastroenterol Nutr, 2004;384:392-400 Rao A, Coan A, Welsh JE, Barclay WW, Koumenis C, Cramer SD p27Kip1 is Essential for the Antiproliferative Action of 1,25-dihydroxyvitamin
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but not Immortalized Mouse Fibroblasts J Biol Chem 2002 Oct 4; 27740: 37301-6 Epub 2002 Aug 5 Rao A, Coan A, Welsh J-E, Barclay WW, Koumenis C, Cramer SD 2004 Vitamin D Receptor and p21/WAF1 are Targets of Genistein and 1,25-dihydroxyvitamin D3 in Human Prostate Cancer Cells Cancer Research: 64:2143-2147 Schwartz GG, Eads D, Rao A, Cramer SD, Willingham MC, Chen TC, Jamieson DP, Wang L, Burnstein KL, Holick MF, Koumenis C Pancreatic cancer cells express 25-hydroxyvitamin D-1 alpha-hydroxylase and their proliferation is inhibited by the prohormone 25-hydroxyvitamin D3 Carcinogenesis 2004 Jun;256:1015-26 Shively CA, Register TC, Grant KA, Johnson JL, Cline JM Effects of dietary isoflavone aglycones on the reproductive tract of male and female mice Toxicol Pathol 2004; 321:91-99 Simon NG, Kaplan JR, Hu S, Register TC, Adams MR Increased aggressive behavior and decreased affiliative
behavior in adult male monkeys after long-term consumption of diets rich in soy protein and isoflavones Horm Behav, 2004;454:278-284 Steck-Scott S, Paskett E, Cooper MR, Quandt S, DeGraffinreid C, Bradham K, Kent L, Self M, Boyles D Carotenoids, vitamin A and risk of adenomatous polyp recurrence in the Polyp Prevention Trial Int J Cancer, 2004;1122:295-305 Stredrick DL, Stokes AH, Worst TJ, Freeman WM, Johnson EA, Lash LH, Aschner M, Vrana KE Manganese-induced cytotoxicity in dopamine-producing cells Neurotoxicology, 2004;254:543-553 Surette ME, Edens M, Chilton FH, Tramposch KM Dietary echium oil increases plasma and neutrophil long-chain n-3 fatty acids and lowers serum triacylglycerols in hypertriglyceridemic humans J Nutr 2004 Jun;1346:1406-11 Wood, CE, Cline JM, Anthony MS, Register TC, Kaplan JR Adrenocortical effects of oral estrogens and soy isoflavones in female monkeys J Clin Endocrinol Metab 2004; 895:2319-2325 Wood CE, Register TC, Anthony MS, Kock ND, Cline JM Breast and
uterine effects of soy isoflavones and conjugated equine estrogens in postmenopausal female monkeys J Clin Endocrinol Metab 2004; 897:3462-3468 Young MV, Schwartz GG, Wang L, Jamieson DP, Whitlatch LW, Flanagan JN, Lokeshwar BL, Holick MF, Chen TC The prostate 25-hydroxyvitamin D-1 alphahydroxylase is not influenced by parathyroid hormone and calcium: implications for prostate cancer chemoprevention by vitamin D Carcinogenesis, 2004;256:967971 Zhao R, Planalp RP, Ma R, Greene BT ,Jones BT, Brechbiel MW, Torti FM, Torti SV Role of zinc and iron chelation in apoptosis mediated by tachpyridine, an anticancer iron chelator Biochem Pharmacol, 2004;679:1677-1688 Aschner M, Erikson KM, Dorman DC Manganese dosimetry: species differences and implications for neurotoxicity Crit Rev Toxicol, 2005;351:1-32 Canner PL, Furberg CD, Terrin ML ,McGovern ME Benefits of niacin by glycemic status in patients with healed myocardial infarction Am J Cardiol, 2005;952:254257 19
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2005
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Djousse L, Arnett DK, Carr JJ, Eckfeldt JH, Hopkins PN, Province MA, Ellison RC Dietary linolenic acid and adjusted QT and JT intervals in the National Heart, Lung, and Blood Institute Family Heart Study Circulation, 2005;11122:2921-2926 Djousse L, Rautaharju PM, Hopkins PN, Whitsel EA, Arnett DK, Eckfeldt JH, Province MA, Ellison RC Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study J Am Coll Cardiol, 2005;4510: 1716-1722 Erikson KM, Dorman DC, Lash LH, Aschner M Persistent alterations in biomarkers of oxidative stress resulting from combined in utero and neonatal manganese inhalation Biol Trace Elem Res, 2005;1042:151-164 John EM, Schwartz GG, Koo J, Van Den Berg D Sun exposure, vitaminD receptor gene polymorphisms, and risk of advanced prostate cancer Cancer Res,
2005;6512:5470-5479 Kemper KJ, Super E, Woods C, Nagaraj S Cranberry use among pediatric nephrology patients Ambulatory Pediatrics, 2005;54:249-252 Land MH, Rouster-Stevens K, Woods CR, Cannon ML, Cnota J, Shetty AK Lactobacillus sepsis associated with probiotic therapy Pediatrics, 2005;1151: 178-181 Lim D, Morgan RJ, Akman S, Margolin K, Carr BI, Leong L, Odujinrin O, Doroshow JH Phase I trial of menadiol diphosphate vitamin K-3 in advanced malignancy Invest New Drugs, 2005;233:235-239 Lippman SM, Goodman PJ, Klein EA, Parnes HL, Thompson IM Jr, Kristal AR, Santella RM, Probstfield JL, Moinpour CM Designing the Selenium and Vitamin E Cancer Prevention Trial SELECT J Natl Cancer Inst, 2005;972:94-102 Poole C, Peters U, Ilyasova D, Arab L Black tea and cardiovascular disease [reply to letter] Int J Epidemiol, 2005;342:483 Register TC, Cann JA, Kaplan JR, Williams JK, Adams MR, Morgan TM, Anthony MS, Blair RM, Wagner JD Effects of soy isoflavones and conjugated equine estrogens on
inflammatory markers in atherosclerotic, ovariectomized monkeys J Clin Endocrinol Metab, 2005;903:1734-1740 Sun H, Berquin IM and Edwards IJ Omega-3 polyunsaturated fatty acids regulate syndecan 1 expression in human breast cancer cells Cancer Res, 2005, 65: 10 4442-4447 Swann AC, Birnbaum D, Jagar AA, Dougherty DM, Moeller FG Acute Yohimbine increases laboratory-measured impulsivity in normal subjects Biol Psychiatry, 2005;5710:1209-1211 Wajih N, Sane DC, Hutson SM, Wallin R Engineering of a recombinant vitamin Kdependent gamma-carboxylation system with enhanced gamma-carboxyglutamic acid forming capacity: evidence for a functional CXXC redox center in the system J Biol Chem, 2005;28011:10540-10547
Legal, Ethical and Policy Issues
2005 Cohen MH, Hrbek A Davis RB, Schachter SC, Boyer E, Kemper KJ, Eisenberg DM Emerging credentialing practices, malpractice liability policies, and guidelines 20 August 1, 2005
2005 2005
governing complementary and alternative medical practices and
dietary supplement recommendations Arch Intern Med 2005;165:289-95 Cohen MH, Kemper KJ Complementary therapies in pediatrics: a legal perspective Pediatrics 2005;1153:774-780 Cohen MK, Kemper KJ, Stevens L, Hashimoto D, Gilmour J Pediatric use of a complementary therapy: ethical and policy choices Pediatrics, 2005 in press
Lifestyle
2004 Brach JS, Simonsick EM, Kritchevsky S, Yaffe K, Newman AB The association between physical function and lifestyle activity and exercise in the Health, Aging and Body Composition study J Am Geriatr Soc, 2004;524:502-509 Buchanan CK, High KP Nutrition, aging, and infection Clin Geriatr, 2004;122:4453 Colbert LH, Visser M, Simonsick EM, Tracy RP, Newman AB, Kritchevsky SB, Pahor M, Taaffe DR, Brach J Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study J Am Geriatr Soc, 2004;527:1098-1104 Danhauer SC, Oliveira B, Myll J, Berra K, Haskell W Successful dietary changes in
cardiovascular risk reduction intervention are differentially predicted by biopsychosocial characteristics Prev Med, 2004;394:783-790 Dennis LK, Snetselaar LG, Smith BJ, Stewart RE, Robbins MEC Problems with the assessment of dietary fat in prostate cancer studies Am J Epidemiol, 2004;1605:436-444 Erkkila AT, Lichtenstein AH, Mozaffarian D, Herrington DM Fish intake is associated with a reduced progression of coronary artery atherosclerosis in postmenopausal women with coronary artery disease Am J Clin Nutr, 2004;803:626632 Focht BC, Brawley LR, Rejeski WJ, Ambrosius WT Group-mediated activity counseling and traditional exercise therapy programs: effects on health-related quality of life among older adults in cardiac rehabilitation Ann Behav Med, 2004;281:52-61 Grzywacz JG, Keyes CLM Toward health promotion: physical and social behaviors in complete health Am J Health Behav, 2004;282:99-111 Hauret KG, Bostick RM, Matthews CE, Hussey JR, Fina MF, Geisinger KR, Roufail WM Physical
activity and reduced risk of incident sporadic colorectal adenomas: observational support for mechanisms involving energy balance and inflammation modulation Am J Epidemiol, 2004;15910:983-992 Kritchevsky SB A review of scientific research and recommendations regarding eggs J Am Coll Nutr, 2004;236 Suppl:596S-600S Landi F, Cesari M, Onder G, Lattanzio F, Gravina EM, Bernabei R Physical activity and mortality in frail, community-living elderly patients J Gerontol A Biol Sci Med Sci, 2004;59A8:833-837 Lee JS, Kritchevsky SB, Tylavsky FA, Harris T, Everhart J, Simonsick EM, Rubin SM, Newman AB Weight-loss intention in the well-functioning, community-dwelling elderly: associations with diet quality, physical activity, and weight change Am J Clin Nutr, 2004;802:466-474 21 August 1, 2005
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Mellen PB, Palla SL, Goff DC Jr, Bonds DE Prevalence of nutrition and exercise counseling for
patients with hypertension: United States, 1999 to 2000 J Gen Intern Med, 2004;199:917-924 Messier SP, Loeser RF, Miller GD, Morgan TM, Rejeski WJ, Sevick MA, Ettinger WH Jr, Pahor M, Williamson JD Exercise and dietary weight loss in overweight and obese older adults with knee osteoarthritis: the Arthritis, Diet, and Activity Promotion Trial Arthritis Rheum, 2004;505:1501-1510 Mozaffarian D, Psaty BM, Rimm EB, Lemaitre RN, Burke GL, Lyles MF, Lefkowitz D, Siscovick DS Fish intake and risk of incident atrial fibrillation Circulation, 2004;1104:368-373 Nicklas BJ, Ambrosius W, Messier SP, Miller GD, Penninx B, Loeser RF, Palla S, Bleecker E, Pahor M Diet-induced weight loss, exercise, and chronic inflammation in older, obese adults: a randomized controlled clinical trial Am J Clin Nutr, 2004;794:544-551 Patterson RE, Prentice RL, Beresford S,Caan B, Chlebowski RT, Granek IA, Haines PS, Hubbell FA, Jackson R Dietary adherence in the Womens Health Initiative Dietary Modification Trial J Am
Diet Assoc, 2004;1044:654-658 Rocco MV Poor nutritional status and inflammation: mechanisms and treatment Semin Dial, 2004;176:425-426 Simon NG, Kaplan JR, Hu S, Register TC, Adams MR Increased aggressive behavior and decreased affiliative behavior in adult male monkeys after long-term consumption of diets rich in soy protein and isoflavones Hormones and Behavior 2004; 454:278-284 You T, Berman DM, Ryan AS, Nicklas BJ Effects of hypocaloric diet and exercise training on inflammation and adipocyte lipolysis in obese postmenopausal women J Clin Endocrinol Metab, 2004;894:1739-1746 Mozaffarian D, Longstreth WT Jr, Lemaitre RN, Manolio TA, Kuller LH, Burke GL, Siscovick DS Fish consumption and stroke risk in elderly individuals: the Cardiovascular Health Study Arch Intern Med, 2005;1652:200-206 Mozaffarian D, Rimm EB, Psaty BM, Siscovick DS, Lemaitre RN, Burke GL, Lyles MF, Lefkowitz D Letter regarding article by Mozaffarian et al, Fish intake and risk of incident atrial fibrillation:
response [reply to letter] [online only] Circulation, 2005;1114:e37 van Gool CH, Penninx B, Kempen G, Rejeski WJ, Miller GD, van Eijk J, Pahor M, Messier SP Effects of exercise adherence on physical function among overweight older adults with knee osteoarthritis Arthritis Rheum, 2005;531:24-32
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2005
Mind Body and Music
2004 2004 Feldman JB The neurobiology of pain, affect and hypnosis Am J Clin Hypn, 2004;463:187-200 Kemper KJ, Martin K, Block SM, Shoaf R, Woods C Attitudes and Expectations about Music Therapy for Premature Infants in a Neonatal Intensive Care Unit Alt Ther Health Med, 2004, Mar-Apr; 102:50-54 22 August 1, 2005
2004 2004
2004
Shively CA, Bethea CL Cognition, mood disorders, and sex hormones ILAR J 2004; 45:189-199 Shively CA, Register TC, Grant KA, Johnson JL, Cline CM Effects of social status and moderate alcohol consumption on mammary gland and endometrium of surgically menopausal monkeys Menopause 2004;114:389-399 Stern RM, Vitellaro K, Thomas M,
Higgins SC, Koch KL Electrogastrographic biofeedback: a technique for enhancing normal gastric activity Neurogastroenterol Motil, 2004;166:753-757
Other
2004 Hess, SM, Shaw, C, Anderson, J, Shaw, E DNA Damage and Cytotoxicity of Therapeutic Grade Essential Oils Journal of Cancer Integrative Medicine 12: 41, 2004 Kemper KJ, Woods CR, Yard B, Cohen D, McLean T, Atkinson M Heart Rate Variability in Pediatric Patients with Leukemia - a brief report J Cancer Integr Med Summer;23:137-143 Schroeder EB, Whitsel EA, Evans GW, Prineas RJ, Chambless LE, Heiss G Repeatability of heart rate variability measures J Electrocardiol, 2004;373: 163-172
2004
2004
23 August 1, 2005
Review articles, chapters and books N21 Biofield therapies/Spirituality: Acupuncture, Reiki, Healing Touch, Qigong, Prayer
2004 Kemper KJ, Kelly EA Treating Children with Therapeutic and Healing Touch Pediatric Annals, 2004; 334:248-252 Hess S and Clewell S Energy Medicine in Integrative Oncology, Principles and Practice,
edited by Matt Member, MD, Parthenon, CRC Press, 2005 in press Hess, S, Shaw E, Stark N Research and Evidence in Integrative Oncology, Principles and Practice, edited by Matt Member, MD, Parthenon, CRC Press, 2005, in press
2005 2005
Herbs and Dietary Supplements
2004 Birt DF, Anthony M, Alekel DL, Hendrich S Soybean and the prevention of chronic human disease In: Boerma HR, Sprecht JE eds, Soybean Monograph, 3rd edition, American Society of Agronomy, Madison, WI in press Clarkson TB, Appt SE Cardiovascular effects of dietary soy In: Watson RR, Preedy VR, eds Nutrition and Heart Disease: Causation and Prevention Boca Raton, FL, CRC Press 2004:215-236 Gardiner P, Dvorkin L, Kemper KJ Supplement Use Growing Among Children and Adolescents Pediatric Annals 2004; 334:227-232 Kemper KJ, Singla M, Gardiner P Herbs and Dietary Supplements for Asthma Clinical Pulmonary Medicine, 2005;122:67-75 Gardiner P and Kemper KJ Herbs and Supplements for GI Disorders Contemporary Pediatrics, 2005, in
press Kemper KJ and Gardiner P Herbal Medicine, Chaper 713 Nelsons Textbook of Pediatrics 18th Edition, in press Surette ME, Tramposch KM, Chilton FH Dietary echium oil increases tissue long chain n-3 fatty acids and lowers serum triacylglycerols in hypertriglyceridemic humans [abstract] FASEB J, 2005;195 Pt II:A972
2004
2004 2005 2005 2005 2005
Legal, Ethical and Policy Issues
2004 Kemper KJ, Cohen M Ethics meet complementary and alternative medicine: New light on old principles Contemporary Pediatrics 2004; 213:61-72
Mind Body
2005 2005 Kemper KJ and Danhauer SC Music as Therapy Southern Medical Journal, 2005:983:282-288 Kemper KJ, Jennings D Consider the benefits of music therapy for your patients Contemporary Pediatrics 2005;222:59-66 24 August 1, 2005
Other
2004 Block KI, Burns B, Cohen AJ, Dobs AS, Hess SM, Vic Point-counterpoint: using clinical trials for the evaluation of integrative cancer therapies Integr Cancer Ther 31:66-81, 2004 Kemper KJ, McLellan MC, Highfield ES
Massage therapy and acupuncture for children with chronic pulmonary disease Clinical Pulmonary Medicine, 2004; 114:242-250 Kemper KJ and McLean TW Complementary and Alternative Medical Therapies in Pediatric Oncology In Pizzo PA and Poplack DG, eds Principles and Practice of Pediatric Oncology, 5th ed Philadelphia, PA: Lippincott Williams Wilkins In Press Kemper KJ Overview of complementary and alternative medical therapies, part I Up to Date in Pediatrics, 2004;101 CD-ROM Kemper KJ Overview of complementary and alternative medical therapies, part II Up to Date in Pediatrics, 2004; 101 CD-ROM Kemper KJ Nonpharmacologic approaches to treating chronic pain Audio-Digest Pediatrics Kemper KJ Asthma: adjuncts for easier breathing nonpharmacologic approaches to therapy Audio-Digest Pediatrics Kemper KJ and Walcott C Integrative Pediatrics; Chapter 307 Pediatrics, edited by Lucy Osborn, Thomas DeWitt, Lewis First, and Joseph Zenel, 2005: 1959-1964
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Abstracts N14 not cited elsewhere Epidemiology/Health Services
2005 DeMattia A, Kemper KJ Who receives appropriate recommendations about complementary and alternative medical therapies? Abstract presentation at 2005 Eastern Society for Pediatric Research Annual Meeting, Old Greenwich, CT March 6, 2005 Bell RA, Suerken CK, Grzywacz JG, Lang W, Quandt SA, Arcury TA CAM use for health treatment among adults with diabetes in the US Diabetes, 2005 54 Supplement 1
2005
Clinician/Patient Relationships and Communication
2005 Guest C, Hawes D, Khanna V, Feldman S Use of a consultation/prescription form to improve communication with referring doctors [abstract] J Am Acad Dermatol, 2005;523 Suppl 1:P108
Herbs and Dietary Supplements
2004 2004 Lees CJ, Register TC, Kaplan JR Soy increases bone density in skeletally mature, premenopausal monkeys Menopause 2004;116 Pt 1:652 Register TC, Kaplan JR, Adams MR, Anthony MS, Williams JK, Blair RM, Wagner JD, Clarkson TB Soy isoflavone
consumption is associated with reduced serum soluble vascular cell adhesion molecule-1 sVCAM-l in postmenopausal monkeys J Nutr 2004;1345:1244S Borden LS, Clark PE, Miller A, Lee WR, Hu J, Stindt D, Torti FM, Hall MC Prospective dose-escalation trial of lycopene in men with recurrent prostate cancer following definitive local therapy [abstract] J Urol, 2005;1734 Suppl:275 Dougherty DM, Marsh DM, Mathias CW, Morgan CJ, Bradley DM, Badawy AA-B Impulsive behavior differences following combined alcohol and Ltryptophan depletion/loading manipulation [abstract] J Psychopharmacol, 2005;183 Suppl:A32 Erikson KM, Jones SR, Aschner M Brain manganese accumulation due to toxic exposure is mediated by the dopamine transporter [abstract] FASEB J 2005;195 Pt II:A1033-A1034 Gu L, Prior RL, Fang N, Ronis MJ, Clarkson TB, Badger TM Interspecies differences of isoflavone metabolic phenotypes in female rats, pigs, monkeys and humans [abstract] FASEB J, 2005;194 Pt I:A446 Kaplan JR, Wagner J Low social
status and soy protein increase insulin sensitivity in premenopausal monkeys [abstract] Am J Phys Anthropol, 26 August 1, 2005
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2005;126S40:126-127 Kavanagh KA, Zhang L, Davis M, Rudel LL, Williams JK, Wagner JD Comparison of dietary soy and estrogen effects on hepatic cholesterol metabolism in ovariectomized cynomolgus monkeys [abstract] FASEB J, 2005;195 Pt II:A1460 Wood CE, Register TC, Cline JM Soy isoflavone effects on endogenous estrogen metabolism in the breast Gene Expression in Reproduction: The 14th Annual Meeting of the Triangle Conference on Reproductive Biology UNC-Chapel Hill, Chapel Hill, NC February, 2005
Lifestyle
2005 Liese AD, Schulz M, Du S, DAgostino R Jr, Wolever TM Dietary glycemic index, glycemic load, carbohydrate intake and plasma lipids: the Insulin Resistance Atherosclerosis Study [abstract] Circulation, 2005;11114:218
Other
2005 Kemper KJ, Larrimore D, Dozier J, Woods C Electives in Complementary Medicine: Are we
preaching to the choir? Poster presentation at Pediatric Academic Society Meeting, Washington, DC May 2005
27 August 1, 2005
Holistic and Integrative Medical Education
Since 2004, holistic and Integrative Medicine has been a THEME in the undergraduate medical curriculum PA students 2004 Kemper Introduction to Holistic and Integrative Medicine WFUSM 7/28/04 2004 Mentored Research projects PA Student: Erica Kelly 2003-2004 Effect of music on heart rate variability in pediatric oncology patients Mentor: Kemper Cherise Kaper 2003-2004 The efficacy of Reiki alone and with chemotherapy in a colon cancer xenograft model Mentor: Hess Medical Students mentored research: 2004 Sarah Barbour: Use of dietary supplements by women with NVP Mentor: Kemper Elizabeth Super Cranberry use among pediatric nephrology patients Mentor: Kemper and Nagaraj April Gay: The effects of essential oils on lung and colon cancer cell lines Mentor: Hess 2005 Barry A Mindfulness Based Stress Reduction for obesity
Mentor:Dailey Annie Bouhairie: HRV in response to music in pediatric oncology patients Mentor: Kemper Cases for case-based teaching include CAM content
1st year medical students
2nd year medical students 8 Cases in the Organ System/Physiology courses include CAM content 2003-2004 Elective: Kemper and Larrimore, Therapeutic and Healing Touch - 7 week Elective 2004 Barnes, L The Cultural Formation of the Physician: Implications for Practice WFUSM September 30, 2004 lecture 2004 2005 Nutrition Course Includes lecture on herbs and dietary supplements 2004 MAAP Student lecture Kemper CAM or Holistic and Integrative Healing September 2, 2004 2004 MAAP Student lecture on Spirituality Suggs 2004 2005 Elective: Kemper and Larrimore, Therapeutic and Healing Touch - 7 week Elective 3rd year medical students 2004 2005 Kemper: Cultivating Compassion required seminars for 3rd year students on pediatrics 28 August 1, 2005
Seniors Phase V 2004 Therapeutic and Healing Touch Massage
Mindfulness Based Stress Reduction Reiki Residents 2004 Pediatric Resident orientation: Kemper: Introduction to Emotional Self-management and Healing Touch June 29, 2004
Fellows 2004 2005 Mentored Research opportunities
Faculty/staff development Dietary supplements GCRC and Grand Rounds lectures visiting professors 75-150 faculty/staff each 1/04 Abram Hoffer, MD, PhD Orthomolecular Psychiatry Psychiatry, Canada Booke Visiting Professor for Herbs and Dietary Supplements 3/04 Reinhold Vieth, PhD Vitamin D Cancer Center, Toronto Booke Visiting Professor for Herbs and Dietary Supplements 5/04 Joseph Hibbeln, MD Omega 3 fatty acids in depression and aggression Pediatric Grand Rounds, NIH Booke Visiting Professor for Herbs and Dietary Supplements 5/04 Joseph Hibbeln, MD The Clinical Effects of Omega-3 Fatty Acids GCRC Lecture WFUSM Winston Salem, NC National Institutes of Health Booke Visiting Professor for Herbs and Dietary Supplements 9/04 Connie Weaver, MD Soy and Bone Health
Comparative Medicine, Indiana Booke Visiting Professor for Herbs and Dietary Supplements 3/05 Robert Fletcher, MD Multivitamins: Do they really improve health? Booke Visiting Professor for Herbs and Dietary Supplements GCRC WFUSM Harvard Medical School
CAM-Community lecture series 50 -100 participants each 1/04 3/04 5/04 9/10/04 11/5/04 Ronny Bell, PhD CAM Epidemiology in NC Todd Smith, DC - Homeopathy Jeff Williamson, MD Ginkgo and Memory Study GEMS Graham A Myofascial Release: Gentle Relief for Acute and Chronic Pain Isley-Landreth B Guided Meditation: Respite for Body, Mind and Spirit 29 August 1, 2005
5/05
Mitch Krucoff Duke The MANTRA Project: Music, Imagery, Touch and Prayer Therapy for Interventional Cardiac Care 5/12/05 Caryl Guth, MD Magnetic Therapy: Clinical Experience and Evidence Other 2004
Suggs Drumming Demonstration; CAM Community Mixer, WFUSM, March 29, 2004 Tai Chi weekly classes for faculty and staff Piedmont Plaza Yoga 2 weekly classes Hanes Bldg and Comp
Rehab Pilates weekly classes for faculty and staff Comp Rehab
National education: 2004 2005 e-curriculum on Herbs and Dietary Supplements 1,200 enrollees Kemper and Northwest AHEC
30 August 1, 2005
Local CME/Grand Rounds/NW AHEC Presentations to Professionals N22
Biofield therapies/Spirituality: Acupuncture, Reiki, Healing Touch, Qigong, Prayer
2004 2004 2004 2004 Isley-Landreth-Lap Labyrinths/Tools for Balance, Spirituality and the Body/Mind Spirit, CPE Residents, WFUBMC July 12, 2004 Isley-Landreth Chi Kung, Music, Meditation and Cymatics Spirituality and the Body/Mind/Spirit, CPE Residents, WFUBMC July 19, 2004 Isley-Landreth, Larrimore Healing Touch Clinic for Staff Hospice and Palliative Care Center, Winston Salem, NC July 19, 2004 Isaacs, A sponsored by NWAHEC and the Synergy Clinical Consulting Services Physical Emotional Intelligence: Clinical applications of the Enneagram September 11, 2004 Wake Forest University Larrimore D Nursing Inservice on Healing Touch 48
participants February 8 and February 23, 2005 Larrimore D Healing Touch Presentation Brenner Childrens Hospital Nursing Unit Managers March 28, 2005 Larrimore D Healing Touch Demonstration for Nurses National Nurses Week WFUSM May 23, 2005
2005 2005 2005
Epidemiology/Health Services
2004 Barbour S Prevalence of CAM and home remedies among women with nausea and vomiting of pregnancy Presented at Student Research Day Mentor: Kemper
Herbs and Dietary Supplements
2004 2004 Kemper KJ Herbal Jeopardy WFUSM Alumni Weekend WFUSM Winston Salem, NC October 8, 2004 Kemper KJ Herbal Jeopardy Grand Rounds Moses Cone Hospital Greensboro, NC August 11, 2004 Kemper KJ Herbal Jeopardy Grand Rounds, Family Medicine, UNC January 29, 2005 Fletcher R Harvard Medical School, visiting professorEvidence-Based Medicine: In the mainstream but threatened by zealots Piedmont Plaza Epidemiology Seminar WFUSM Winston-Salem, NC March 17, 2005 Kemper KJ Herbal Jeopardy Grand Rounds, Pediatrics, UNC May 6,
2005
2005 2005
2005
31 August 1, 2005
Mind Body
2004 2004 2004 2004 Isley-Landreth Impact of Stress/Relaxation Responses on the Body/Mind/Spirit Mind/Body Medicine Seminar, CPE Residents, WFUBMC January 26, 2004 Isley-Landreth Guided Meditation in the Management of Pain Mind/Body Medicine Seminar, CPE Residents, WFUBMC February 10, 2004 Isley-Landreth Making Lap Labyrinths/Tools for Balance Brain Tumor Support Group, Cancer Services Winston Salem, NC April 13, 2004 Isley-Landreth Guided Meditation in the Management of Pain Adolescent Sickle Cell Support Group, WFUBMC June 8, 2004 Erica Kelly Poster Music and HRV In Pediatric Oncology Patients UNC Conference on Integrated Medicine March 18-19, 2005 Erica Kelly Poster Music and HRV in Pediatric Oncology Patients WFUSM Student Poster Presentation April, 2005
2005 2005
Spirituality
2004 Barnes L Spirituality, Religion and Pediatrics: Intersecting Worlds of Healing WFUSM Pediatric Grand Rounds September 29, 2004 Boston Medical
Center visiting professor
Other
2004 Barnes L Cultures, Clinics, and Qualitative Research: Notes from a Medical Anthropologist GCRC Noon Seminar September 29, 2004 Boston Medical Center Hess, et al Alternative Medicine, Five Keys to Wellness, Interdisciplinary Study 130, Team presentation lectures on complementary alternative medicine, energy medicine and essential oils Continuing Education Program, Northwest Area Health Education Center NWAHEC, Wake Forest University Health Sciences, Winston-Salem, NC
2004
32 August 1, 2005
Regional, National and International Presentations N42
Biofield therapies/Spirituality: Reiki, Healing Touch, Therapeutic Touch, Qigong, Prayer
2004 2004 Kemper Therapeutic Touch The Ecology of Healing, Global Medicine Education Foundation, Petaluma, CA March 14, 2004 Kemper Therapeutic Touch national invitational mentorship program Pumpkin Hollow Craryville, NY, July 16-23, 2004 Kemper KJ Therapeutic Touch Pediatric Academic Society Meeting Special interest
group in pain Washington, DC May 13, 2005 Kemper KJ, Larrimore D Cultivating Compassion: Tools from Therapeutic and Healing Touch Pediatric Academic Society Meeting Workshop Washington, DC May 16, 2005
2005 2005
Communication, Clinician-Patient Relationship, Cultural Competence
2004 Blue, AV, Crandall, SJ Creating and closing the loop on gender and cultural biases in health care for the medical school curriculum Southern Group on Educational Affairs of the Association of American Medical Colleges Regional Meeting, April 15-17, 2004, Savannah, Georgia Blue, AV, Crandall, SJ Enhancing cultural competency curricula through faculty development Southern Group on Educational Affairs of the Association of American Medical Colleges Regional Meeting, April 1517, 2004, Savannah, Georgia Crandall, SJ, Davis, S Empowering Empathy Through the Medical Humanities The Generalists in Medical Education Conference, Boston, MA, November 6-7, 2004 Crandall, SJ, Spangler, JG, Walker, K, Vaden, K, Marion,
GS Description of a Training Program to Prepare Tobacco-specific Standardized Patient Instructors Society of Teachers of Family Medicine Annual Spring Conference, New Orleans, LA, April 30-May 4, 2005 Koontz-Anthony, J Marion, GS, Crandall, SJ Using the Common Ground Communications Model to Provide More Culturally Competent Patient Care Southern Group on Educational Affairs of the Association of American Medical Colleges Regional Meeting, Winston Salem, North Carolina, April 7-10, 2005 Marion, GS, Palla, SL, Rigsbee, B, Crandall, SJ Learner Attitudes Toward the Patient-Provider Relationship: Fostering Provider Accountability to an Increasingly Diverse Demography American 33 August 1, 2005
2004
2004
2005
2005
2005
Educational Research Association Conference, Montréal, Québec, Canada, April 11-15, 2005
Epidemiology/Health Services
2005 2005 Arcury TA CAM Use in North Carolina Vegetarian Society of Forsyth County March 1, 2005 Dunn EC, Yu KJ, Danhauer SC, McQuellon RP Miller BE
Characteristics of complementary and alternative medicine users in the outpatient gynecologic oncology clinic 2005 Annual Meeting on Womens Cancer March 2005 Rosen L, Garnecho A, Patrick PA CAM use by families of children with Autistic Spectrum Disorder SPR/APA May, 2005
2005
Herbs and Dietary Supplements
2004 Blair RM, Cline JM, Wood CE, Adams MR Dietary Phytoestrogens: Beneficial and Adverse Effects on the Reproductive System 13th Annual Meeting of the Triangle Consortium for Reproductive Biology Environmental Protection Agency, Research Triangle Park, February 7, 2004 Clarkson TB - Soy Equol? as Co-Postmenopausal Hormone Therapy The American College of Obstetricians and Gynecologists 52nd Annual Meeting Philadelphia, PA May 1-2, 2004 Clarkson TB Soy and Tibolone A Nearly Ideal Postmenopausal Therapy? Fourth Annual Purdue-UAB Botanicals Center Symposium Botanicals and Age-Related Disease Birmingham, AL February 26, 2004 Edwards I Differential effects of delivery of n-3 fatty
acids to human breast cancer cells by low density lipoproteins versus albumin International Research Conference on Food, Nutrition and Cancer of the American Instute for Cancer Research, Washington DC July 15, 2004 Kemper KJ Herbal Jeopardy Super CME 2004, Orlando FL April 30, 2004 Vitolins M- Can soy isoflavones replace traditional hormone replacement therapy? Annual meeting of the Tennessee Dietetic Association 2004 Clarkson TB Soy as Complementary HT 2nd Annual OB/GYN Research Symposium at Meharry Medical College Kemper KJ Herbal Jeopardy UNC Conference on Integrative Medicine, Chapel Hill, NC March, 2005 Kemper KJ Herbal Jeopardy Advances in Pediatrics 16th Annual Las Vegas Postgraduate Pediatric Meeting Las Vegas NV April 15, 2005 Kemper KJ Herbal Jeopardy Symposia Medicus, St Thomas, VI May 20, 2005 34 August 1, 2005
2004
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2004 2004
2005 2005 2005 2005
2005
Torti S Potential role for iron chelation in the chemopreventative activity of curcumin Annual Meeting for
the Society for Free Radicals in Biology and Medicine 2005
Mind Body
2004 Danhauer SC Mind-body approaches in cancer care Spring Oncology Symposium, Gibbs Regional Cancer Center, Spartanburg Regional Health System, Spartanburg, SC April 2004 Kemper KJ Complementary and Alternative Medicine - The Yin and the Yang of Healing Work AAP Super CME Orlando FL April 30, 2004 Shively C Social stress and disease susceptibility in nonhuman primates Conference on Allostatic Load and the Response to Traumatic Injury National Institute of General Medical Sciences Bethesda, MD March 2003 Shively C Social inequalities in health: a comparative perspective Texas Program for Society and Health Houston, TX January 13, 2004 Dailey M, McCarty A Experiential Training in Mindfulness Based Stress Reduction to OR Nurses February 23, 2005 Danhauer SC, Rutherford CA, Ashbury DY, Marier B, McQuellon RP, Lovato JF, Miller BE Music or guided imagery for women undergoing colposcopy: Effects on anxiety pain levels
5th Annual UNC Integrative Medicine Conference, Chapel Hill, NC March, 2005
2004 2004
2004
2005 2005
Other
2004 Kemper KJ Complementary and Alternative Therapies for Chronic Pulmonary Conditions in Children 6th International Congress on Pediatric Pulmonology Lisbon, Portugal March 2, 2004 Kemper KJ - Complementary and Alternative Medicine AAP Super CME, Orlando, FL May 1, 2004 Kemper KJ Holistic Pediatric Health Care: Caring for the Whole Child Kahn Family Foundation International Conference on Pediatrics Kennebunkport, ME September 18, 2004 Kemper KJ Pediatric Integrative Medicine Summit Pediatric Integrative Medicine Summit St Paul, MN October 8, 2004 Kemper KJ Kemper-Visiting Professor Childrens Memorial Hospital Chicago, IL November 12, 2004 Kemper KJ Whats the Buzz?: Talking with Patients about Complementary Therapies Advances in Pediatrics 16th Annual Las Vegas Postgraduate Pediatric Meeting Las Vegas NV April 15, 2005 Kemper KJ Non Pharmacologic Approaches to Treating
Chronic Pain Advances in Pediatrics 16th Annual Las Vegas Postgraduate Pediatric Meeting Las Vegas NV April 16, 2005 Kemper KJ Asthma Adjuncts for Easier Breathing Non-Pharmacologic 35 August 1, 2005
2004 2004
2004 2004
2005
2005
2005
2005
2005 2005
2005
Approaches to Therapy Advances in Pediatrics 16th Annual Las Vegas Postgraduate Pediatric Meeting Las Vegas NV April 17, 2005 Kemper KJ Holistic and Integrative Medicine A General Pediatric Perspective Symposia Medicus Conference, St Thomas, VI May 19, 2005 Kemper KJ ADHD: Diagnosis and Treatment Symposia Medicus, St Thomas, VI May 19, 2005 Kemper KJ Asthma Adjuncts for Easier Breathing Non-Pharmacologic Approaches to Therapy Symposia Medicus St Thomas, VI May 21, 2005 Williams J Integration of Complementary and Alternative Medicine into Clinical Practice: Evidence-Based Medicine John Hopkins June 8, 2005
36 August 1, 2005
Clinical N12 Biofield therapies/Spirituality: Acupuncture, Healing Touch, Qigong, Prayer
2004 2004
2004 Larrimore D Healing Touch class offered by NWAHEC October 28-29, 2004 Seeber S, Graham A Dao Yin Yoga Best Health 1/14/05 Graham ATai Chi Sickle Cell Adolescent Support Group, Winston Salem, NC July 6, 2004 Larrimore D Healing Touch - Tenderly Touching Your Tuesdays Brenner Childrens Hospital Oncology Section Monthly sessions Larrimore D Gatherings of Grace Free Healing Touch Clinic held monthly
2005 2005
Herbs and Dietary Supplements
2005 Fletcher R Vitamins Supplements Best Health, WFUSM March 16, 2005
Mind Body
2004 2005 2005 2005 Massage Therapy interest group Pediatrics established in September, 2004 Feldman J Functional Restoration Program - Hypnosis/Guided Imagery WFUBMC Melcher S, Boyce D, Dean C, Godfrey M, Howell D Massage Therapy WFUSM Fitness Center Arts for Life non-profit Art and Music Therapy provided to children at Brenners Childrens Hospital - 70 hours a week Value estimated at 70,000 Arts for Life non-profit Art and Music Therapy provided to adult patients at
the Comprehensive Cancer Center Child Life Program Pet therapy provided at Brenner Childrens Hospital
2005 2005
37 August 1, 2005
Community Outreach N18 Biofield therapies/Spirituality: Acupuncture, Reiki, Healing Touch, Prayer
2004 2004 Hess S - Reiki as a Complementary Therapy Best Health 55 lecture series, Kernersville YMCA, Kernersville, NC , May 12, 2004 Larrimore D Healing Touch for Health Professionals Northwest AHEC Winston-Salem, NC October 22-23, 2004 Graham A, Seeber S Best Health Program QiGong and Prayer on February 24, 2005
2005
Herbs and Dietary Supplements
2004 2004 2004 2004 2004 2004 Kemper K Herbal Remedies BestHealth, Winston Salem, NC March 19, 2004 Kemper K Supplementing Youth BestHealth, Winston Salem, NC September 22, 2004 Vitolins M - Soy, the joy of it BestHealth Winston-Salem, NC 2004 Vitolins M - What should you eat? First Church of the Nazarene WinstonSalem, NC, 2004 Vitolins M - Healthy eating and good table manners Best Health Kids,
Winston-Salem, NC 2004 Vitolins M - Alternative treatments to hormone replacement therapy Womens Health conference, Forsyth County Health Department, Winston-Salem, NC 2004 Fletcher R Multivitamins BestHealth March 16, 2005 Harvard Medical School, Booke visiting professor for Dietary Supplements
2005
Mind Body
2005 2005 2005 Melcher, S Medicine of Massage Best Health April 1, 2005 Isley-Landreth B Guided Meditation Workshop Your Yoga April 3, 2005 Dailey M Teacher Development Intensive in Mindfulness Based Stress Reduction, Worcester, MA Center for Mindfulness in Medicine, Health Care and Society April 6-14, 2005
Other
2004 2004 Hess S - Bridging the Gap Between Conventional and Complementary Medicine, Shepherd Center, Winston-Salem, NC, April 1, 2004 Hess S - Bridging the Gap Between Conventional and Complementary Medicine, Connecting the Rhythms: A networking event for the CAM and Medical Communities, Invited Speaker, NWAHEC, Winston-Salem, 38 August 1, 2005
2004 2004 2004
NC,
March 29, 2004 Hess S - Complementary and Alternative Medicine and Cancer, Cancer Services, Winston-Salem, NC, February 17, 2004 Kemper K Complementary and Alternative, Holistic and Integrative Medicine at WFUSM Rotary Club, Winston Salem, NC March 9, 2004 Smith TA Homeopathy; Douglas D Brendle Integrative Medicine Seminar Series WFUSM March 10, 2004
39 August 1, 2005
National Advisory Boards
2001 2004 2001 - present 2002 - present 2003 - present 2003 - present 2003 present 2004 - present 2005 present 2005 present Kemper KJ- American Academy of Pediatrics, Task Force on CAM Kemper KJ - Scientific Advisory Council, Massachusetts College of Pharmacy and Allied Health Sciences, Boston, Massachusetts Kemper KJ- Ambulatory Pediatric Association Guidelines on Residency Core Curriculum Kemper KJ - American Medical Student Association, CAM Education Panel Kemper KJ- J Miller Integrative Medicine Initiative, Northwestern University Kemper KJ - Many Streams Healing Systems, non-profit
corporation, Rome, Georgia Kemper KJ - Complementary and Alternative Research and Education, Alberta, Canada Kemper KJ - Advisory Board for Aspen Center for Integrative Health Kemper KJ Chair Provisional Section for Complementary, Holistic and Integrative Medicine American Academy of Pediatrics
Editorial Boards
2002 present 2003 present 2003 present 2004 present 2005 - present Kemper - Ambulatory Pediatrics Kemper - Alternative Medicine Alert Newsletter Hess Journal of Cancer Integrative Medicine Kemper - Explore: Journal of Science and Healing Kemper - Journal of Cancer Integrative Medicine
Honors
2004 2005 Kemper K -YWCA Woman of Vision Award Kemper K Finalist, Bravewell Leadership Award in Integrative Medicine
40 August 1, 2005
Source:cancer.gov
